This guide is designed to help new users set up and operate the latest Gen2 XDAQ™ system for recording and analyzing neural signals. It provides a streamlined guideline on hardware, software, system checks, data acquisition and analysis. Whether you're exploring the system or have already purchased, the guide also helps you identify the suite of products best suited to your experimental needs. Following the outlined workflow and linked resources will support a smooth setup process and help you troubleshoot common issues with confidence.